Assay Data Scientist

Job title:

Assay Data Scientist

Company

Lightcast Discovery

Job description

Our mission is to push the boundaries of complex cell analysis. Using the Lightcast platform we are working with major pharmaceutical companies, leading academic institutes, and innovative biotechnology leaders. Together, using our next generation microfluidic platform, we are making advances towards new science, unique clinical approaches, new therapies, and innovative products.The Lightcast platform allows precise, highly flexible, and massively parallel control of tens to hundreds of thousands of picolitre volume microdroplets using beams of light and powerful software logic. By sequentially combining droplets containing different cells, antibodies, cancer drugs, reporters and /or other reagents, we can perform complex workflows and assays at scale with a flexibility far beyond what is currently possible on any cell analysis platform.About the roleLightcast are a life-science startup developing a unique platform for massively parallel processing of single cell assay operations that will revolutionise conventional drug discovery workflows and cell-based research. We are hiring a non-lab based assay data scientist to support our biology team in advancing analysis capabilities in imaging, flow cytometry, automation and statistics.This role will involve working closely with interdisciplinary teams to support product development and deliver customer projects. With a strong background in complex data interrogation and statistical analysis to support assay development and medium / high throughput screening, the successful candidate will work in collaboration with lab scientists to support development of new applications for drug discovery, drive optimisation and troubleshooting of cell-based assays and carry out custom experimental analysis for specific workflows and collaboration partners.Key aspects of the role include:

• Data Analysis Expertise for Assay Development & Screening: Designing, optimising, and analysing data from cell-based assays, including imaging and flow cytometry data, to identify hits and measure assay performance.
• Data Interpretation & Visualization: Conducting complex analysis on single cell data and generating actionable insights using statistical methods and visualization tools.
• Collaborative Research: Partnering with cross-functional research teams to develop and validate new instrument applications, providing input into robust experimental design, interrogating data to support interpretation and effectively communicating data-driven results in project meetings.
• Mentorship & Training: Providing guidance and supporting science team members to enhance overall team capabilities in data analysis, statistics and experimental design.

This role requires a data-driven mindset, strong problem-solving skills, and the ability to communicate complex results clearly to a range of stakeholders.We would expect you to have:

• Advanced degree in biological sciences or other relevant field.
• Proven track record of developing and applying complex analysis methods to support scientific interpretation of large cell-based screening data sets, including high content imaging and flow cytometry.
• Experience in new technology and assay development.
• Demonstrated ability to conduct collaborative research and extract insights from datasets using mathematical, statistical, and computational approaches.
• Excellent mentorship and guidance skills.
• Effective communication skills with a broad range of stakeholders.

It would be advantageous for you to have:

• Understanding of drug discovery and experience with analysis of data sets from high to medium throughput cell-based screens.
• Previous practical experience or strong knowledge of cell assay development and troubleshooting concepts.
• Working knowledge of infectious diseases, neuroscience, and immunology.

Personal Attributes:

• Technology-focused. Passionate about developing a career in the biotech industry.
• Scientifically curious with a strong attention to detail, a problem-solving mindset and a passion for bringing clarity from complex datasets.
• Excellent communication and collaboration skills, with a demonstrated ability to work effectively in cross-functional teams.

We offer a generous benefits package including:

• 26 days holiday, plus Public Holidays
• Flexible working hours
• Pension contribution matched up to 7%
• Private medical insurance
• Income protection
• Life insurance
• Subsidized gym membership and weekly cross fit sessions
• Access to Cycle to Work and Technology schemes
• Enhanced family leave policies

At Lightcast, we recruit on a rolling basis, meaning we carry on recruiting until we find the right person for the role being advertised. We tend to compare individuals to the role specification rather than to each other.About LightcastLightcast Discovery is a bio-tools company developing a platform that combines the flexibility to analyse a wide range of cell types and assays with precise control over droplet number, occupancy, location and movement. Working with major pharmaceutical companies and leading academic institutes. Together, using our next generation microfluidic platform, we are driving scientific innovation, developing unique therapeutic approaches, and forging a path to exciting new scientific discoveries. Learn more about Lightcast Discovery at https://www.lightcast.bio/.Lightcast Discovery is committed to equal employment opportunity regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.At Lightcast, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way in our book. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background and what you can bring to Lightcast Discovery.
Recruitment & Staffing Agencies: Lightcast Discovery does not accept unsolicited resumes from any source other than directly from candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Lightcast or its employees is strictly prohibited unless contacted directly by Lightcast Discovery’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Lightcast Discovery, and Lightcast Discovery will not owe any referral or other fees with respect thereto.

Expected salary

Location

Cambridge

Job date

Tue, 24 Dec 2024 23:53:25 GMT

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